Journal of Thyroid Disorders & Therapy offers the most comprehensive and reliable information pertaining to the latest developments in the field. The Journal also believes in advancing new hypotheses and opinions by means of its high quality Reviews, Perspectives, and Commentaries. Thus, the content published in the journal is original and comprehensive.

Graves’ disease is the commonest cause of thyrotoxicosis and it is much less common in males. Also, there is scanty information about the clinical characteristics of males with Graves’ disease. The objectives of the study were to determine the frequency of males with Graves’ disease seen by the Endocrinology unit of a tertiary hospital and describe their clinical characteristics.

 Graves’ disease is the commonest form of hyperthyroidism in both males and females. It represents about 50-80% of cases of hyperthyroidism. It is an autoimmune disease characterized by the interaction between the thyroid stimulating hormone receptor antibodies (TRAb) and the thyroid stimulating hormone receptor. The classical symptoms of hyperthyroidism include weight loss despite increased appetite, heat intolerance, irritability, insomnia, sweatiness, hyperdfaecation, palpitations, muscular weakness and menstrual irregularity. Clinical signs include diffuse goitre, fine resting tremor, tachycardia, hyperreflexia, lid lag, warm, smooth skin and proximal myopathy. Less common findings include atrial fibrillation and thyroid bruit reflecting the marked increase in thyroid vascularity.

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Denise Williams
Editorial Manager     
Journal of Thyroid Disorders & Therapy
E-mail id: Thyroiddisorders@emedscholar.com